Anhydrous cerium chloride can be used to prepare cerium and cerium salts, aluminum-magnesium olefin polymerization catalysts, rare earth trace element fertilizers, medicines, etc., mainly used in petroleum catalysts, automobile exhaust catalysts, intermediates and other industries. It is the main raw material for the preparation of rare earth cerium by electrolysis and metal thermal reduction. The rare earth ammonium sulfate double salt is dissolved in sodium hydroxide, oxidized in air, and then pickled with dilute hydrochloric acid. Now let's learn about the applications of anhydrous cerium chloride?
As we all know, nucleophilic addition reaction is an important step in organic synthesis and has broad application prospects. However, this reaction is often accompanied by alcoholization, reduction, condensation, and condensation of olefins, which α, β-unsaturated aldehydes, and ketones affect the yield of adduct products. Its addition can effectively prevent these side reactions, improve the yield and shorten the reaction time. Because Ce3+ has a strong affinity for oxygen, it binds to the oxygen atom on the carbonyl group more easily than Li or mg. The alkalinity of organocerium reagents is lower than that of organolithium and Grignard reagents. It is easy to coordinate with carbonyl oxygen to activate the carbonyl group, which is conducive to the addition reaction of nucleophiles. Therefore, organocerium reacts with high-resistance aldehydes and ketones to form corresponding alcohols, which can synthesize a variety of tertiary alcohols. The results showed that alkyl, naphthenyl, aryl, heterocyclic aryl and α, β-unsaturated substituted acyl groups could react with vinyl magnesium bromide without side reactions. The synthesis of the product and its application in the pharmaceutical industry have a good application prospect. It can promote a variety of organic reactions and is used in organic synthesis and the synthesis of pharmaceutical intermediates. The addition of anhydrous cerium chloride to Grignard reagent or organolithium prevents side reactions of carbonyl nucleophilic addition reactions, improving yield and selectivity. This method can synthesize a variety of tertiary alcohols, and the reaction of organocerium with nitrile can prepare tertiary methylamine.